Name:Wang Wan associate professor
Hometown:Jiujiang, Jiangxi
Education
2007-2011-Heilongjiang University-B.S. in Chemistry
2012-2018-Clemson University-Ph.D in Chemistry
Publications
1. Wan, W.; Smith, R, C. “GADIPY: The Heavier Main Group Analogues of BODIPY”J. Am. Chem. Soc.2019. DOI: 10.1021/jacs.9b03235
2. Wan, W.; Bedford, M. S.; Conrad, C. A.; Yang, X.; Hu, L.; Chumanov, G.; Smith, R. C. “Influence of Sidechains Composition On Polythiophene Properties and Supramolecular Assembly of Anionic Polythiophene Derivatives”J. Polym. Sci. A,20182018, 57, 1173-1179
3. Yang, X.; Bedford, M. S.;Wan, W.; Conrad, C. A.; Colter, E. F.; Freeman, E. H.; Wilson, C.; Hu, L.; Chumanov, G.; Whitehead, K.; Smith, R. C. “Inter-cation Spacing and Side Chain Effects on Phosphonium Polymers: Thermal, Supramolecular and Bactericidal Properties”J. Polym. Sci. A,2019, 57. 24-34.
4. Wan, W.; Yang, X.; Smith, R. C. “Convenient Synthetic Route to Tetraarylphosphonium PolyelectrolytesviaPalladium-Catalyzed P-C Coupling of Aryl Triflates and Diphenylphosphine”J. Polym. Sci. A,2017, 55, 1984–1990
5. Wan, W.; Yang, X.; Smith, R. C. “Convenient Route to Tetraarylphosphonium Polyelectrolytes via Metal-Catalysed P–C Coupling Polymerization of Aryl Dihalides and Diphenylphosphine”ChemComm,2017, 53, 252-254
6. Yang, X., Conrad, C. A.,Wan, W.; Bedford, M. S.; Hu, L.; Chumanov, G., Smith, R. C. “Influence of Spacer Length and Rigidity on Properties of Phosphonium Polymers and on Their Supramolecular Assembly with a Conjugated Polyelectrolyte”J. Mater. Chem. C,2015, 3, 4537-4544.
7. Wan, W.; Zhu, Z.; Huo, L.; Deng, Z.; Zhao, H.; Gao, S. “Syntheses, Structures and Luminescent Properties of Lithium(I)-Sulfonate Complexes Constructed from Ortho-Hydroxyl Arenedisulfonic Acids: Structural Evolution Tuned by the pH, Coordination Geometry and Modes”CrystEngComm,2012, 14, 5274-5284
8. Zhu, Z.;Wan, W.; Deng, Z.; Ge, Z.; Huo, L.; Zhao, H.; Gao, S. “Structure Modulations in Luminescent Alkaline Earth Metal-Sulfonate Complexes Constructed from Dihydroxyl-1,5-Benzenedisulfonic Acid: Influences of Metal Cations, Coordination Modes and pH Value”CrystEngComm,2012,14, 6675-6688
9. Fang, X.; Deng, Z.; Huo, L.;Wan, W.; Zhu, Z.; Zhao, H.; Gao, S. “New Family of Silver(I) Complexes Based on Hydroxyl and Carboxyl Groups Decorated Arenesulfonic Acid: Syntheses, Structures, and Luminescent Properties”Inorg. Chem.,2011, 50, 12562–12574
10. Wan, W.; Jin, W.; Huang, Y.; Xia, Q.; Bai, Y.; Lyu, H.; Liu, D.; Dong, X.; Li, W.*; Liu, Y.*; Monitoring the Dynamics of Proteome Aggregation in Live Cells Using a Solubilized and Noncovalent Analogue of Fluorescent Protein Chromophores. Anal. Chem., 2021, 93(3), 1717-1724.
11. Wan, W.; Huang, Y.; Xia, Q.; Bai, Y.;Jin, W.;Wang, M.; Lyu, H.; Tang, Y.; Dong, X.; Gao, Z.; Zhao, Q.; Zhang, L.; Liu, Y.*; Covalent Probes for Aggregated Protein Imaging via Michael Addition. Angew. Chem. Int. Ed. Engl., 2021, 60, 11335-11343.(Hot paper)
12. Bai, Y.; Wan, W.*; Huang, Y.; Jin, W.; Lyu, H.; Xia, Q.; Dong, X.; Gao, Z.; Liu, Y.*; Quantitative Interrogation of Protein Co‐aggregation using Multicolor Fluorogenic Protein Aggregation Sensors. Chem.Sci., 2021, 12, 8468–8476. (Most popular 2021 chemical biology articles)
13. Wan, W.;╪ Zeng, L.;╪ Jin, W.; Chen, X.; Shen, D.; Huang, Y.; Wang, M.; Bai, Y.; Lyu, H.; Dong, X.; Gao, Z.; Wang, L.; Liu, X.; Liu, Y.*;A Solvatochromic Fluorescent Probe Reveals Polarity Heterogeneity upon Protein Aggregation in Cells.Angew. Chem. Int. Ed. Engl., 2021, 60, 25865-25871.
14. Dong, X.;╪ Wan, W.;╪ Zeng, L.; Jin, W.; Huang, Y.; Shen, D.; Bai, Y.; Zhao, Q.; Zhang, L.; Liu, Y.*; Gao, Z.*; Regulation of Fluorescence Solvatochromism to Resolve Cellular Polarity upon Protein Aggregation. Anal. Chem., 2021, 93 (49), 16447-16455.
Self-introduction
Wang worked on investigation of polyelectrolytes and fluorescent molecules during his Ph.D career. The research focused on new synthetic routes to polyelectrolytes which can be applied on alkaline fuel cell, and developing analogues of BODIPY dyes as applicable fluorescent probes. Wang joined Dr. Liu ‘s group on April 2019 as post-doctoral fellow. Currently he is working on design and synthesis of novel fluorophores applying on detection of misfolded protein. He also works on fluorescence-based high throughput screening to obtain desired medicine. Wang plays tennis and goes to gym a lot when he has free time.
Award
2019 DICP Excellent Post-doctor
