Name: Di Shen assistant professor
Hometown: Liaoning, Dalian
Education
2010-2014 Shenyang Pharmaceutical University B.S. in Pharmacy
2014-2017 Shenyang Pharmaceutical University M.S. in Medicinal Chemistry
2017-2020 Shenyang Pharmaceutical University Ph.D in Medicinal Chemistry
Publications
1. Di Shen, Youjun Xu, Shi-Liang Shi. A bulky chiral N-heterocyclic carbene palladium catalyst enables highly enantioselective Suzuki-Miyaura Cross-Coupling reactions for the synthesis of biaryl atropisomers. J. Am. Chem. Soc. 2019, 141, 14938.
2. Di Shen, Wu-Bin Zhang, Zhiyang Li, Shi-Liang Shi* and Youjun Xu*. Nickel/NHC-catalyzed enantioselective cyclization of pyridones and pyrimidones with tethered alkenes. Adv. Synth. Catal. 2020, 362, 1125.
3. Zi-Chao Wang, Di Shen, Jian Gao, Xian Jia, Youjun Xu*, Shi-Liang Shi*. Base-catalysed reductive relay hydroboration of allylic alcohols with pinacolborane to form alkylboronic esters. Chem. Commun. 2019, 55, 8848.
4. Shen, D.; Jin, W.; Bai, Y.; Huang, Y.; Lyu, H.; Zeng, L.; Wang, M.; Tang, Y.; Wan, W.; Dong, X.; Gao, Z.; Piao, H.; Liu, X.; Liu, Y.*; Rational Design of Crystallization Induced Emission Probes to Detect Amorphous Protein Aggregation in Live Cells. Angew. Chem. Int. Ed. Engl., 2021, 60, 16067-16076.
5. Shen, D.; Bai, Y.; Liu, Y.*; Chemical Biology Toolbox to Visualize Protein Aggregation in Live Cells. ChemBioChem, 2021, accepted.
Self-introduction
Di worked on investigation of new chiral NHC ligands and application on important asymmetric catalytic reaction during his Ph.D career. Di joined Dr. Liu’s group on July 2020 as post-doctoral fellow. Currently he is engaged in discovery new chemistry on the surface of separated protein. Baseball and badminton are his favorite sports.
